Fig. 2. Inhibition of ASC attenuate the visfatin-induced inflammasomes activation in podocytes. Summarized data showing the fold change of caspase-1 activity (A) and IL-1β production (B) in podocytes with or without stimulation of visfatin and/or Asc siRNA transfection. N=5 each group. Ctrl: Control, Vehi: Vehicle, Scram: Scramble, Asc si: Asc siRNA, Casp-1: Caspase-1. * Significant difference (P<0.05) compared to the control group; ^# Significant difference (P<0.05) compared to the visfatin (vehicle) group.